Term paper 11195

C Pk11195 Synthesis Essay -

Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Suwon, Republic of Korea.

Google Case Study Essay - 11195 Words

The pharmacological agent 1-(2-Corophenyl-N-methylpropyl)-3-isoquinolinecarboxamide (PK11195) is the prototypical land of the 18-k Da Translocator Protein (TSPO) but at μM concentrations deactivates the oncoprotein Bcl-2 increasing the efficiency of chemotherapeutic agents and promoting the Ca2 -dependent macro-autophagy (or autophagy).

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